The Importance of the Entourage Effect

Have you ever wondered why Palmetto Harmony uses the whole plant instead of isolated cannabidiol (CBD)? It seems like a product touting that it is “Pure CBD” would be stronger right? In actuality, this could not be further from the truth.  Products using whole plant extract can be almost an order of magnitude stronger than isolated CBD.  The importance of the entourage effect comes into play.

For example, we have some people who are using Palmetto Harmony that were previously using isolated CBD. When using CBD isolate, they were dosing 200mg. After switching to Palmetto Harmony, they reported feeling relief from just 20mg CBD. The reason for this increased strength is a powerful synergistic interaction that takes place. This effect is known in the cannabis arena as the “entourage effect”. The entourage effect refers to the positive interaction of the almost 480 natural compounds unique to Cannabis sativa L .  This includes 66 cannabinoids120 terpenes and a whole host of other potentially beneficial substances present in the whole plant which are removed when using isolated “pure” CBD (1).

Many of these compounds are beneficial in their own right. They can also work together with CBD boosting its efficacy. This effect is what allows those using a whole plant product to use significantly smaller doses.  This means the benefits are comparable to a much larger dose of isolated CBD. Whole plant products also garner added benefits of the other important compounds present in the Cannabis sativa L plant.

Products using whole plant extract can be almost an order of magnitude stronger than isolated CBD.

“Entourage effect” is a term first used by Dr. Raphael Mechoulam, a brilliant organic chemist. He was the first person to be able to isolate not only CBD, but also its better known relative Δ9-tetrahydrocannabinol (THC) way back in 1963! Dr. Mechoulam has also headed up research on the endogenous cannabinoid system.  His postdoctoral researchers isolated a compound we all have in our bodies; a compound which he dubbed anandamide (from the sanskrit ananda meaning bliss). This compound itself could be effective in the treatment of depression and anxiety. It is also mimicked by CBD and other cannabinoids in the brain (2).

Thank you so much to all of you out there in the PH Nation who have helped spread the word about Palmetto Harmony. Keep up the positive synergy as we will too!



3 thoughts on “The Importance of the Entourage Effect

  1. Randall Snyder, Jr says:

    This is pending infirmation. At times I encounter folks who are skeptics and I could really help them a lot of I can reference the research that supports the statements made in this post. Can you provide links to the source infirmation? It would be a great update to this blog post to add the links to it as well.

  2. Pingback: Palmetto Aura E-Liquid: The BEST Whole Plant Vape Oil - Palmetto Harmony | Best Whole Plant Hemp Products

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